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MET ablation during hippocampus development alters the time course of the LTP and long-time depression (LTD) development, the two major forms of synaptic plasticity

After homogenization, 1 mL of extraction solution (isopropanol: HO: HCl = 2:1:0.002) was added, and the mixture was sonicated for 30 min at 4 C in the dark using a KQ5200DE ultrasonic cleaner (Kunshan Shumei Ultrasonic Instruments, Suzhou, China)

A375 cells were cultured until 3050% confluence, then treated with a complete growth medium containing 0.1 M doxorubicin (Sigma D1515)